{"id":1033,"date":"2021-02-25T11:42:09","date_gmt":"2021-02-25T03:42:09","guid":{"rendered":"https:\/\/mygenome.asia\/?p=1033"},"modified":"2021-02-25T11:52:01","modified_gmt":"2021-02-25T03:52:01","slug":"some-neandertal-genes-in-people-today-may-protect-against-severe-covid-19","status":"publish","type":"post","link":"https:\/\/mygenome.asia\/zh\/blog\/some-neandertal-genes-in-people-today-may-protect-against-severe-covid-19\/","title":{"rendered":"Some Neandertal genes in people today may protect against severe COVID-19"},"content":{"rendered":"<p>Inherited DNA from our ancestors can play varying roles in immune response to disease<\/p>\n\n\n\n<p>Some genetic variants inherited from Neandertals may protect against developing severe <a href=\"https:\/\/mygenome.asia\/zh\/mygenome-authorized-lab-for-covid-19\/\" target=\"_blank\" rel=\"noreferrer noopener\">2019\u51a0\u72b6\u75c5\u6bd2\u75c5<\/a>.<\/p>\n\n\n\n<p>A new study looked at a stretch of <a href=\"https:\/\/mygenome.asia\/zh\/whole-genome-sequencing\/\" target=\"_blank\" rel=\"noreferrer noopener\">DNA<\/a> on chromosome 12 where a haplotype \u2014 a cluster of genetic variants that are inherited together \u2014 that affects susceptibility to the coronavirus is located. For each copy of the Neandertal haplotype a person inherited, the risk of needing intensive care fell approximately 22 percent, researchers report in the March 2 Proceedings of the National Academy of Sciences.<\/p>\n\n\n\n<p>The variants may affect the activity or function of genes involved in a biochemical chain reaction that ends with the destruction of viral RNA, including the coronavirus\u2019s. The protective variants are largely absent among people in sub-Saharan Africa, where few people carry genes inherited from Neandertals. About 25 to 30 percent of present-day people of Asian and European ancestry carry the protective variants. Some Black people in the Americas also inherited the protective haplotype, presumably from Asian, European or Native American ancestors.<\/p>\n\n\n\n<p>Previously, researchers had found that a different haplotype on chromosome 3 that was inherited from Neandertals increases the risk of severe disease (SN:10\/2\/20). The results show that genetic inheritance can help or hinder the immune response to disease.<\/p>\n\n\n\n<p>This article was originally published on: https:\/\/www.sciencenews.org\/article\/coronavirus-some-neandertal-genes-protection-severe-covid-19<\/p>","protected":false},"excerpt":{"rendered":"<p>Inherited DNA from our ancestors can play varying roles in immune response to disease Some genetic variants inherited from Neandertals may protect against developing severe COVID-19. A new study looked at a stretch of DNA on chromosome 12 where a haplotype \u2014 a cluster of genetic variants that are inherited together \u2014 that affects susceptibility [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1034,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[22],"tags":[],"class_list":["post-1033","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news_updates"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Some Neandertal genes in people today may protect against severe COVID-19 - MyGenome<\/title>\n<meta name=\"description\" content=\"Inherited DNA from our ancestors can play varying roles in the immune response to disease - 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